I run the report with no filters I get data. I put a filter on the field to show if R is in the filed and D is in the other Field this data is in there when I put no filters but when I put the filter on the field which does indeed have this in there No data will pull. 

if there is data that meets both criteria, the idea that comes to mind is that there are spaces in the field, so it doesn't match....might try trimming the fields.

I was thinking either a join enforcement issue (hence my original question) or what Lockwelle suggested that a field is actually an "R " or something like that.
I would try each part separate to see if each piece can work by itself. What do you get if you only filter for R? Then only for D?
If one breaks it try and trim it like lockwelle suggested.